Answer : 2. "Autoimmune disease"
Explanation :

Australian researchers have recently developed a solution to the lupus defect. Lupus, an autoimmune disease, causes the immune system to damage organs and tissues, causing inflammation of the skin, joints, blood, and vital organs such as the kidneys and heart. Its origin is unknown, thought to be caused by a mixture of genetic, hormonal, and environmental factors. Lupus mainly affects women. Variants include systemic lupus erythematosus (SLE), discoid lupus, subacute cutaneous lupus, drug-induced lupus, and rare neonatal lupus associated with maternal antibodies in newborns.