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Q: Which of the following statements about ddntps is true?

  • 1
    They have a hydrogen at the 3’ carbon of the sugar.
  • 2
    DNA polymerase can add a new dNTP to a 3’ ddNTP.
  • 3
    They have a free 3’-hydroxyl group on the ribose sugar.
  • 4
    They have an oxygen at the 2’ carbon of the ribose sugar.
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Answer : 1. "They have a hydrogen at the 3’ carbon of the sugar."
Explanation :

Answer: A) They have a hydrogen at the 3’ carbon of the sugar. Explanation: ddNTPs - Dideoxynucleotides and abbreviated as ddNTPs.   They are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing.   They have a hydrogen at the 3’ carbon of the ribose sugar.

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