Which of the following is the primary source of Mitochondrial Coxiella effector (MceF) protein?
5Q:
Which of the following is the primary source of Mitochondrial Coxiella effector (MceF) protein?
- 1Bacteriatrue
- 2Germsfalse
- 3Virusfalse
- 4Calciumfalse
- Show AnswerHide Answer
- Workspace
Answer : 1. "Bacteria"
Explanation :
Recently researchers have unveiled the mitochondrial Coxiella effector F (MceF), an antioxidant protein produced by the gram-negative intracellular bacterium Coxiella burnetii. MceF supports human cell health despite heavy bacterial load. Upon invading host cells, Coxiella burnetii releases MceF interacting with glutathione peroxidase 4 (GPX4) in the mitochondria. This interaction enhances mitochondrial function, preventing cell damage and death associated with pathogen replication in mammalian cells. The newly discovered protein shows potential therapeutic applications.